SYNB 1891
Alternative Names: SYN-STING; SYNB-1891Latest Information Update: 19 Apr 2022
At a glance
- Originator Synlogic
- Developer AbbVie; Synlogic
- Class Anti-inflammatories; Antineoplastics; Bacteria; Gene therapies; Immunotherapies
- Mechanism of Action STING1 protein stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Discontinued Inflammatory bowel diseases; Lymphoma; Solid tumours
Most Recent Events
- 19 Apr 2022 Discontinued - Phase-I for Lymphoma (Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (Intratumoural) (Synlogic pipeline, December 2021)
- 19 Apr 2022 Discontinued - Phase-I for Lymphoma (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Monotherapy, Second-line therapy or greater) in USA (Intratumoural) (Synlogic pipeline, December 2021)
- 19 Apr 2022 Discontinued - Phase-I for Solid tumours (Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (Intratumoural) (Synlogic pipeline, December 2021)