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Tuvusertib - EMD Serono Research & Development Institute

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Drug Profile

Tuvusertib - EMD Serono Research & Development Institute

Alternative Names: ATR kinase inhibitor - EMD Serono Research & Development Institute; M-1774; MSC2584415A; VRT-1363004; VXc-400

Latest Information Update: 28 May 2025

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At a glance

  • Originator EMD Serono Research & Development Institute
  • Developer EMD Serono Research & Development Institute; Merck KGaA
  • Class Amides; Antineoplastics; Imidazoles; Pyrazoles; Pyridines; Pyrimidines; Small molecules
  • Mechanism of Action ATR protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Endometrial cancer; Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Phase I/II Non-small cell lung cancer
  • Phase I Solid tumours

Most Recent Events

  • 28 May 2025 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease) in China (PO)
  • 28 May 2025 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease) in Japan (PO)
  • 28 May 2025 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease) in Spain (PO)

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