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PIPE 307

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Drug Profile

PIPE 307

Alternative Names: JNJ 5120; JNJ-89495120; PIPE-307

Latest Information Update: 02 Dec 2025

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At a glance

  • Originator Pipeline Therapeutics
  • Developer Contineum Therapeutics; Janssen Pharmaceutica
  • Class Antidepressants; Small molecules
  • Mechanism of Action Muscarinic M1 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Depressive disorders; Multiple sclerosis

Most Recent Events

  • 20 Nov 2025 Efficacy and adverse events data from phase-II VISTA trial in Multiple sclerosis released by Contineum Therapeutics
  • 04 Aug 2025 Contineum Therapeutics completes the phase-II VISTA trial for Multiple sclerosis in USA (NCT06083753),
  • 28 Apr 2025 Phase-II clinical trials in Depressive disorders (In adults) in USA (PO) (NCT06785012) (Janssen Research & Development pipeline, April 2025)

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