AGLE 102
Alternative Names: AGLE-102; AGLE-103; Extracellular vesicle therapy - Aegle Therapeutics; MSC EVs - Aegle TherapeuticsLatest Information Update: 18 Jul 2025
At a glance
- Originator Aegle Therapeutics
- Class Exosome therapies; Gene therapies; Skin disorder therapies
- Mechanism of Action Collagen type VII replacements
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Phase I/II Burns; Epidermolysis bullosa dystrophica
- Preclinical Graft-versus-host disease
Most Recent Events
- 19 Nov 2024 Aegle Therapeutics completes the Phase-I/II clinical trials in Burns in USA (Topical) (NCT05078385)
- 14 Aug 2024 Phase-I/II clinical trials in Epidermolysis bullosa dystrophica (In adolescents, In adults, In children, In the elderly) in USA (Topical) prior to August 2024 (NCT04173650)
- 08 Jan 2024 Aegle Therapeutics plans a phase I/IIa trial for Epidermolysis bullosa dystrophica in USA (Topical), in Q1 2024 (NCT04173650)