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AGLE 102

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Drug Profile

AGLE 102

Alternative Names: AGLE-102; AGLE-103; Extracellular vesicle therapy - Aegle Therapeutics; MSC EVs - Aegle Therapeutics

Latest Information Update: 20 Aug 2024

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At a glance

  • Originator Aegle Therapeutics
  • Class Exosome therapies; Gene therapies; Skin disorder therapies
  • Mechanism of Action Collagen type VII replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Burns; Epidermolysis bullosa dystrophica
  • Preclinical Graft-versus-host disease

Most Recent Events

  • 14 Aug 2024 Phase-I/II clinical trials in Epidermolysis bullosa dystrophica (In adolescents, In adults, In children, In the elderly) in USA (Topical) prior to August 2024 (NCT04173650)
  • 08 Jan 2024 AGLE 102 is still in preclinical trials for Epidermolysis bullosa dystrophica in USA (Topical)
  • 08 Jan 2024 Efficacy and adverse events data from a phase I/II trial in Burns released by Aegle Therapeutics

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