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CT 0508

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Drug Profile

CT 0508

Alternative Names: Anti-HER2 CAR-M cell therapy - Carisma Therapeutics; CARMA-0508; CT-0508

Latest Information Update: 29 Feb 2024

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At a glance

  • Originator University of Pennsylvania
  • Developer Carisma Therapeutics
  • Class Antineoplastics; Cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; Macrophage replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 29 Feb 2024 CT 0508 is still in phase I trials for Solid tumors in USA (NCT04660929)
  • 28 Feb 2024 No recent reports of development identified for phase-I development in Solid-tumours(Metastatic disease, Second-line therapy or greater) in USA (IV, Infusion)
  • 11 May 2023 Phase-I clinical trials in Solid tumours (Combination therapy, Metastatic disease, Second-line therapy or greater) in USA (IV) (NCT04660929)

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