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AB 1002

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Drug Profile

AB 1002

Alternative Names: AAV2i8.I-1c; AB-1002; BNP116.sc-CMV.I1c; Carfostin™; NAN-101

Latest Information Update: 01 Mar 2025

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At a glance

  • Originator Asklepios BioPharmaceutical; NanoCor Therapeutics
  • Developer Asklepios BioPharmaceutical
  • Class Gene therapies; Heart failure therapies
  • Mechanism of Action Gene transference; Protein phosphatase 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Heart failure

Most Recent Events

  • 13 Feb 2025 Phase-II clinical trials in Heart failure (Treatment-experienced) in Spain (Intracoronary) (NCT05598333)
  • 18 Apr 2024 AB 1002 receives Fast Track designation for Heart failure [Intracoronary,Infusion] (Treatment-experienced) in USA
  • 12 Nov 2023 Efficacy and adverse event data from a phase I trial in Heart failure released by Asklepios Biopharmaceuticals

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