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NMS 293

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Drug Profile

NMS 293

Alternative Names: NMS-03305293; NMS-293; NMS-P293

Latest Information Update: 11 Jun 2025

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At a glance

  • Originator Nerviano Medical Sciences
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Poly(ADP-ribose) polymerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Astrocytoma; Glioblastoma
  • Phase I Ovarian cancer; Small cell lung cancer; Solid tumours
  • No development reported Breast cancer

Most Recent Events

  • 28 Apr 2025 Phase-I clinical trials in Ovarian cancer (Second-line therapy or greater, Combination therapy) (PO) (NCT06930755)
  • 28 Apr 2025 Phase-I clinical trials in Small cell lung cancer (Combination therapy, Second-line therapy or greater) (PO) (NCT06931626)
  • 16 Apr 2025 Nerviano Medical Sciences plans a phase I trial for Ovarian Cancer (Combination therapy, Second-line therapy or greater, Recurrent) in unknown location (PO) (NCT06930755)

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