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Imlunestrant - Eli Lilly and Company/Loxo Oncology

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Drug Profile

Imlunestrant - Eli Lilly and Company/Loxo Oncology

Alternative Names: LY-3484356

Latest Information Update: 04 Jul 2025

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At a glance

  • Originator Eli Lilly and Company
  • Class Antineoplastics; Azetidines; Benzopyrans; Fluorinated hydrocarbons; Heterocyclic compounds with 4 or more rings; Phenyl ethers; Quinolines; Small molecules
  • Mechanism of Action Selective estrogen receptor degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III HER2 negative breast cancer
  • Phase I Endometrial cancer

Most Recent Events

  • 25 Apr 2025 Adverse events, pharmacokinetics and efficacy data from a phase I trial in Breast cancer presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 10 Dec 2024 Pharmacokinetics and adverse events data from phase I trial in Healthy volunteers presented at the 47th Annual San Antonio Breast Cancer Symposium (SABCS-2024)
  • 31 May 2024 Adverse events and efficacy data from a phase I trial in Breast cancer presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)

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