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KPI 012

Drug Profile

KPI 012

Alternative Names: CMB 012; KPI-012

Latest Information Update: 28 Dec 2024

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At a glance

  • Originator Combangio Inc
  • Developer KALA BIO
  • Class Collagens; Eye disorder therapies; Growth factors; Nerve growth factors; Peptide hydrolases; Proteins
  • Mechanism of Action Collagen replacements; Intracellular signaling peptides and protein replacements; Peptide hydrolase replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Corneal injuries
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Corneal injuries
  • Preclinical Limbal stem cell deficiency; Retinitis pigmentosa; Sjogren's syndrome; Stargardt disease

Most Recent Events

  • 28 Dec 2024 No recent reports of development identified for phase-I development in Corneal injuries in Mexico (Ophthalmic, Drops)
  • 08 Aug 2024 Preclinical trials in Retinitis pigmentosa in USA (Ophthalmic)
  • 08 Aug 2024 Preclinical trials in Stargardt disease in USA (Ophthalmic)

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