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MEDI 0618

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Drug Profile

MEDI 0618

Alternative Names: MEDI-0618

Latest Information Update: 25 Jun 2025

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At a glance

  • Originator AstraZeneca
  • Class Analgesics; Monoclonal antibodies
  • Mechanism of Action PAR 2 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Pain
  • Discontinued Migraine

Most Recent Events

  • 05 May 2025 Discontinued - Phase-I for Migraine in United Kingdom (Parenteral) (AstraZeneca pipeline, May 2025)
  • 05 May 2025 Discontinued - Phase-II for Migraine (Treatment-experienced) in Spain, Poland, Netherlands, Italy, Hungary, Germany, Denmark, Czech Republic, USA (Parenteral) (AstraZeneca pipeline, May 2025)
  • 07 Oct 2024 Phase-II clinical trials in Migraine (Treatment-experienced) in USA, Czech Republic, Denmark, Germany, Hungary, Netherlands, Italy, Poland, Spain (Parenteral) (NCT06602479)

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