NRL 1049
Alternative Names: BA 1049; NRL-1049Latest Information Update: 29 Mar 2023
At a glance
- Originator BioAxone Biosciences
- Developer BioAxone Biosciences; Neurelis
- Class Amines; Antineoplastics; Eye disorder therapies; Isoquinolines; Piperidines; Small molecules; Sulfones; Vascular disorder therapies
- Mechanism of Action Rho-associated kinase inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I Cavernous haemangioma
- No development reported Spinal cord injuries
- Discontinued Cancer; Eye disorders
Most Recent Events
- 24 Mar 2023 Phase-I clinical trials in Cavernous haemangioma (In volunteers) in USA (PO)
- 24 Mar 2023 Pharmacodynamics data from a preclinical trial in Cavernous haemangioma released by Neurelis
- 23 Mar 2023 The US FDA approves IND application for NRL 1049 for Cavernous haemangioma in the US, prior to March 2023