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BRL 201

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Drug Profile

BRL 201

Alternative Names: Anti-CD19 CAR-T Cell Therapy - BRL Medicine; BRL-201; CART-19 cells - BRL Medicine; CD19 specific chimeric antigen receptor T-cells - BRL Medicine; CD19-targeted non-viral PD1 site-specific integrated CAR-T cell injection; PD1 specific targeted CD19-CART; PD1 targeting integrated CD19 CART; PD1-CD19-CART; Quikin-CD19-CART

Latest Information Update: 24 Sep 2024

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At a glance

  • Originator Shanghai Bioray Laboratory
  • Developer BRL Medicine
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; Programmed cell death-1 ligand-1 inhibitors; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Non-Hodgkin's lymphoma
  • Phase I B-cell lymphoma

Most Recent Events

  • 13 Jun 2024 Adverse events and efficacy data from a phase-I trial in B-cell lymphoma presented at the 29th Congress of the European Haematology Association (EHA-2024)
  • 31 May 2024 Adverse events and efficacy data from a phase-I trial in B-cell lymphoma presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)
  • 09 Dec 2023 Updated efficacy and adverse events data from a phase I trial in B-cell lymphoma presented at the 65th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2023)

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