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BGB A445

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Drug Profile

BGB A445

Alternative Names: BGB-A445

Latest Information Update: 14 Jun 2025

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At a glance

  • Originator BeiGene
  • Developer BeOne Medicines
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; OX40 receptor agonists; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Non-small cell lung cancer
  • Phase I/II Malignant melanoma; Renal cell carcinoma; Urogenital cancer
  • No development reported Solid tumours

Most Recent Events

  • 28 Mar 2025 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease) in Australia (IV, Infusion)
  • 28 Mar 2025 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease) in Canada (IV, Infusion)
  • 28 Mar 2025 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease) in China (IV, Infusion)

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