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MT 6402

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Drug Profile

MT 6402

Alternative Names: ADC PDL1 - Toxin - Molecular Templates; MT-64-6402; MT-6402

Latest Information Update: 07 May 2025

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At a glance

  • Originator Molecular Templates
  • Class Antineoplastics; Bacterial toxins; Drug conjugates; Immunoglobulin fragments; Immunotoxins; Recombinant fusion proteins; Viral proteins
  • Mechanism of Action Apoptosis stimulants; Cytotoxic T lymphocyte stimulants; Programmed cell death-1 ligand-1 inhibitors; Protein synthesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Head and neck cancer; Non-small cell lung cancer; Solid tumours

Most Recent Events

  • 07 May 2025 Discontinued - Phase-I for Head and neck cancer (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV)
  • 07 May 2025 Discontinued - Phase-I for Non-small cell lung cancer (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV)
  • 07 May 2025 Discontinued - Phase-I for Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV)

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