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MT 6402

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Drug Profile

MT 6402

Alternative Names: ADC PDL1 - Toxin - Molecular Templates; MT-64-6402; MT-6402

Latest Information Update: 14 Nov 2024

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At a glance

  • Originator Molecular Templates
  • Class Antineoplastics; Bacterial toxins; Drug conjugates; Immunoglobulin fragments; Immunotoxins; Recombinant fusion proteins; Viral proteins
  • Mechanism of Action Apoptosis stimulants; Cytotoxic T lymphocyte stimulants; Protein synthesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Head and neck cancer; Non-small cell lung cancer; Solid tumours

Most Recent Events

  • 31 Oct 2024 Molecular Templates terminates a phase I clinical trials in Head and neck cancer (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV), due to sponsor decision (NCT04795713)
  • 31 Oct 2024 Molecular Templates terminates a phase I clinical trials in Non-small cell lung cancer (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV), due to sponsor decision (NCT04795713)
  • 31 Oct 2024 Molecular Templates terminates a phase I clinical trials in Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV), due to sponsor decision (NCT04795713)

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