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Zinlirvimab - Gilead Sciences

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Drug Profile

Zinlirvimab - Gilead Sciences

Alternative Names: 10 1074; 10-1074-LS; 10-1074-LS-J; Anti-HIV-1-neutralising-antibody; GS-2872

Latest Information Update: 18 Jul 2025

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At a glance

  • Originator Rockefeller University
  • Developer Aarhus Universitetshospital; Gilead Sciences; National Institute of Allergy and Infectious Diseases; Rockefeller University; University of California at San Francisco; University of Cologne
  • Class Antiretrovirals; Monoclonal antibodies
  • Mechanism of Action HIV envelope protein gp120 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II HIV-1 infections

Most Recent Events

  • 18 Jul 2025 National Institute of Allergy and Infectious Diseases in collaboration with Gilead Sciences re-initiated a phase I/II trial in HIV 1 infection (Combination therapy,Treatment-experienced) in US and Brazil (NCT06071767)
  • 01 Jul 2025 University of Oxford plans a phase II AbVax trial for HIV infections (Combination therapy) in United Kingdom (IV, infusion) (NCT07054931)
  • 25 Apr 2025 National Institute of Allergy and Infectious Diseases in collaboration with Gilead Sciences suspends a phase I/II trial in HIV 1 infection (Combination therapy,Treatment-experienced) in US and Brazil (NCT06071767)

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