Emiltatug ledadotin - Day One Biopharmaceuticals
Alternative Names: B7-H4 ADC - Mersana Therapeutics; B7-H4 targeting antibody drug conjugate - Mersana Therapeutics; DAY-501; Emi-Le; XMT-1660Latest Information Update: 25 Aug 2026
At a glance
- Originator Mersana Therapeutics
- Class Antibodies; Antineoplastics; Auristatins; Drug conjugates; Immunoconjugates; Immunotoxins; Monoclonal antibodies
- Mechanism of Action Tubulin polymerisation inhibitors
-
Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I/II Solid tumours
Most Recent Events
- 02 Jun 2026 Interim efficacy data from a phase I/II trial in Adenoid cystic carcinoma presented at the 62nd Annual Meeting of the American Society of Clinical Oncology (ASCO-2026)
- 01 Jun 2026 Updated efficacy and adverse events data from a phase I/II trial in Adenoid cystic carcinoma released by Day One Biopharmaceuticals
- 01 Jun 2026 Day One Biopharmaceuticals plans a pivotal phase II trial for Adenoid cystic carcinoma