SEA CD70
Alternative Names: PF-08046040; SEA-CD70Latest Information Update: 14 Jun 2025
At a glance
- Originator Seattle Genetics
- Developer BeOne Medicines; Seagen
- Class Antineoplastics; Immunotherapies; Monoclonal antibodies
- Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I Acute myeloid leukaemia; Myelodysplastic syndromes
Most Recent Events
- 07 Dec 2024 Efficacy and adverse event data from phase I trial in Myelodysplastic syndromes presented at the 66th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2024)
- 14 Dec 2023 Seagen has been acquired by Pfizer
- 22 Jun 2023 SEA CD70 is still in phase I trials for Acute myeloid leukemia (Second-line therapy or greater) in USA (Seagen pipeline, June 2023)