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AVC 101

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Drug Profile

AVC 101

Alternative Names: AVC-101; UniCAR CD123; UniCAR-T-CD123; UniCAR02 T CD123; UniCAR02-T

Latest Information Update: 17 Jun 2026

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At a glance

  • Originator Cellex Patient Treatment
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Discontinued Acute myeloid leukaemia

Most Recent Events

  • 17 Jun 2026 Discontinued - Phase-I for Acute myeloid leukaemia (Second-line therapy or greater) in Germany (IV), before June 2026 (AvenCell Therapeutics pipeline, June 2026)
  • 17 Jun 2026 Discontinued - Phase-I for Acute myeloid leukaemia (Second-line therapy or greater) in Netherlands (IV), before June 2026 (AvenCell Therapeutics pipeline, June 2026)
  • 02 Nov 2023 Updated efficacy and adverse events data from a phase I trial Acute myeloid leukemia presented at the 65th American Society of Hematology Annual Meeting (ASH-2023)

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