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AVC 101

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Drug Profile

AVC 101

Alternative Names: AVC-101; UniCAR CD123; UniCAR-T-CD123; UniCAR02 T CD123; UniCAR02-T

Latest Information Update: 23 Jan 2024

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At a glance

  • Originator Cellex Patient Treatment
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Acute myeloid leukaemia

Most Recent Events

  • 02 Nov 2023 Updated efficacy and adverse events data from a phase I trial Acute myeloid leukemia presented at the 65th American Society of Hematology Annual Meeting (ASH-2023)
  • 05 Apr 2023 AVC 101 is still in phase I trial for Acute myeloid leukaemia (Recurrent, Second-line therapy or greater) in Germany (NCT04230265) (AvenCell Europe pipeline, April 2023)
  • 28 Feb 2023 No recent reports of development identified for phase-I development in Acute-myeloid-leukaemia(Recurrent, Second-line therapy or greater) in Germany (IV, Infusion)

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