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PBCAR 269A

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Drug Profile

PBCAR 269A

Alternative Names: PBCAR 269; PBCAR269A

Latest Information Update: 11 Jan 2024

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At a glance

  • Originator Precision Biosciences
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Multiple myeloma
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Discontinued Multiple myeloma

Most Recent Events

  • 11 Jan 2024 PBCAR 269A is available for licensing as of 09 Jan 2024. www.precisionbiosciences.com
  • 21 Sep 2023 Precision Biosciences terminates a phase I/IIa trial for Multiple myeloma (Combination therapy, Second-line therapy or greater) in USA due to lack of sufficient therapeutic effect (NCT04171843)
  • 21 Sep 2023 Precision Biosciences terminates a phase I/IIa trial for Multiple myeloma (Monotherapy, Second-line therapy or greater) in USA due to lack of sufficient therapeutic effect (NCT04171843)

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