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Roginolisib - iOnctura

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Drug Profile

Roginolisib - iOnctura

Alternative Names: IOA-244

Latest Information Update: 05 Sep 2024

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At a glance

  • Originator Cancer Research Technology; Merck & Co
  • Developer iOnctura
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Phosphatidylinositol 3 kinase delta inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Uveal melanoma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Uveal melanoma
  • Phase II Chronic lymphocytic leukaemia; Myelofibrosis; Non-small cell lung cancer; Peripheral T-cell lymphoma
  • Phase I/II Haematological malignancies; Solid tumours
  • Phase I Malignant melanoma; Mesothelioma; Non-Hodgkin's lymphoma

Most Recent Events

  • 05 Sep 2024 Phase-II clinical trials in Chronic lymphocytic leukaemia (unspecified route) (iOnctura pipeline, September 2024)
  • 05 Sep 2024 Phase-II clinical trials in Myelofibrosis (PO) (iOctura pipeline, September 2024).
  • 05 Sep 2024 Phase-II clinical trials in Non-small cell lung cancer (PO) (iOctura pipeline, September 2024).

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