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Denikitug - Gilead Sciences

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Drug Profile

Denikitug - Gilead Sciences

Alternative Names: GS-1811; JTX 1811

Latest Information Update: 23 Jun 2026

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At a glance

  • Originator Jounce Therapeutics
  • Developer Gilead Sciences
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Regulatory T-lymphocyte inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Colorectal cancer
  • Phase I Solid tumours

Most Recent Events

  • 19 May 2026 Phase-II clinical trials in Colorectal cancer (Combination therapy, Late-stage disease, Second-line therapy or greater, Metastatic disease) in USA, Australia (IV) (NCT07527858)
  • 19 May 2026 Phase-II clinical trials in Colorectal cancer (Late-stage disease, Second-line therapy or greater, Monotherapy, Metastatic disease) in Australia (IV) (NCT07527858)
  • 19 May 2026 Phase-II clinical trials in Colorectal cancer (Second-line therapy or greater, Monotherapy, Late-stage disease, Metastatic disease) in USA (IV) (NCT07527858)

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