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GC 197

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Drug Profile

GC 197

Alternative Names: Anti-CD7 and anti-CD19 chimeric antigen receptor T cell therapy - Gracell Biothechnologies; GC-197

Latest Information Update: 26 Feb 2024

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At a glance

  • Originator Gracell Biotechnology
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II B-cell lymphoma; Precursor B-cell lymphoblastic leukaemia-lymphoma

Most Recent Events

  • 22 Feb 2024 Gracell Biotechnology has been acquired by AstraZeneca
  • 01 Oct 2022 Gracell Biotechnology completes a phase-I/II clinical trial in Precursor B-cell lymphoblastic leukaemia-lymphoma (In adolescents, In children, In adults, In the elderly, Second-line therapy or greater) in China (IV-infusion) (ISRCTN11885863)
  • 01 Oct 2022 Gracell Biotechnology completes a phase-I/II clinical trials in B-cell lymphoma (In children, In adolescents, In adults, In the elderly) in China (IV-infusion) (ISRCTN11885863)

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