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KTI 2338

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Drug Profile

KTI 2338

Alternative Names: KTI-2338

Latest Information Update: 28 Apr 2025

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At a glance

  • Originator Massachusetts General Hospital; National Center for Advancing Translational Sciences
  • Developer Keros Therapeutics
  • Class Antianaemics; Small molecules
  • Mechanism of Action ACVR1 protein inhibitors; Hepcidin modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Iron overload
  • No development reported Anaemia; Fibrodysplasia ossificans progressiva

Most Recent Events

  • 28 Apr 2025 No recent reports of development identified for preclinical development in Anaemia in USA
  • 28 Oct 2023 No recent reports of development identified for preclinical development in Fibrodysplasia-ossificans-progressiva in USA (PO)
  • 09 Jun 2021 Pharmacodynamics data from preclinical studies in Iron overload presented at the 26th Congress of the European Haematology Association (EHA-2021)

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