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TT 11

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Drug Profile

TT 11

Alternative Names: ATLCAR.CD30; CAR.CD30 T cells; CD30 CAR-T; CD30-directed genetically modified autologous T-cell therapy - Tessa Therapeutics; CD30.CAR-T; TT-11; TT11 CD30 CAR T

Latest Information Update: 25 Feb 2026

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At a glance

  • Originator Baylor College of Medicine; University of North Carolina
  • Developer Tessa Therapeutics; University of North Carolina
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Germ cell cancer; Hodgkin's disease
  • Phase I Non-Hodgkin's lymphoma

Most Recent Events

  • 25 Feb 2026 Phase-I development in Hodgkin's-disease (Combination therapy, In adolescents, Recurrent, Second-line therapy or greater, In adults) is still ongoing in USA (Parenteral, Infusion) (NCT05352828)
  • 25 Feb 2026 phase-I development in Non-Hodgkin's-lymphoma (In the elderly, Second-line therapy or greater, In adults) is still ongoing in USA (Parenteral, Infusion) (NCT04526834)
  • 06 Dec 2025 Efficacy and adverse events data from a phase II trial in Hodgkin's-disease presented at the 67th American Society of Hematology Annual Meeting and Exposition Session (ASH-Hem-2025)

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