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Cemacabtagene ansegedleucel - Allogene Therapeutics

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Drug Profile

Cemacabtagene ansegedleucel - Allogene Therapeutics

Alternative Names: ALLO-501.1; ALLO-501A; cema-cel - Allogene Therapeutics; S 95023

Latest Information Update: 07 Aug 2026

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At a glance

  • Originator Cellectis
  • Developer Allogene Therapeutics
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Diffuse large B cell lymphoma
  • Phase I/II Chronic lymphocytic leukaemia

Most Recent Events

  • 29 Jul 2026 Cemacabtagene ansegedleucel - Allogene Therapeutics receives Fast Track designation for Diffuse large B cell lymphoma [Parenteral] (Combination therapy) in USA
  • 29 Jul 2026 Cemacabtagene ansegedleucel - Allogene Therapeutics receives Regenerative Medicine Advanced Therapy (RMAT) status for Diffuse large B cell lymphoma (Combination therapy) in USA
  • 14 Apr 2026 Interim efficacy data from a phase II ALPHA3 trial in Large B cell lymphoma released by Natera

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