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Cemacabtagene ansegedleucel - Allogene Therapeutics

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Drug Profile

Cemacabtagene ansegedleucel - Allogene Therapeutics

Alternative Names: ALLO-501.1; ALLO-501A; cema-cel - Allogene Therapeutics

Latest Information Update: 24 Jun 2024

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At a glance

  • Originator Cellectis
  • Developer Allogene Therapeutics
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Diffuse large B cell lymphoma
  • Phase I/II Chronic lymphocytic leukaemia

Most Recent Events

  • 20 Jun 2024 Allogene Therapeutics plans to submit a Biologics License Application (BLA) for cemacabtagene ansegedleucel
  • 18 Jun 2024 Phase-II clinical trials in Diffuse large B cell lymphoma (Parenteral) in USA (Allogene Therapeutics pipeline, January 2024) (NCT06500273)
  • 08 Feb 2024 Phase-I/II clinical trials in Chronic lymphocytic leukaemia (Second-line therapy or greater) in Canada, Canada, USA (Parenteral) (NCT04416984)

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