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Aflibercept biosimilar - Amgen

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Drug Profile

Aflibercept biosimilar - Amgen

Alternative Names: ABP 938; PAVBLU

Latest Information Update: 10 Mar 2025

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At a glance

  • Originator Amgen
  • Class Antineoplastics; Eye disorder therapies; Immunoglobulin Fc fragments; Immunoglobulin fragments; Recombinant fusion proteins
  • Mechanism of Action Placenta growth factor inhibitors; Vascular endothelial growth factor A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Registered Wet age-related macular degeneration
  • Phase III Retinal disorders

Most Recent Events

  • 30 Jan 2025 Preregistration for Wet age-related macular degeneration in European Union (Intravitreous)
  • 30 Jan 2025 Committee for Medicinal Products for Human Use (CHMP) adopts positive opinions for Aflibercept biosimilar in wet age-related macular degeneration
  • 23 Aug 2024 Registered for Wet age-related macular degeneration in USA (Intravitreous)

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