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LTI 03

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Drug Profile

LTI 03

Alternative Names: Caveolin-1 scaffold protein-derived 7-amino acid peptide; Caveolin-1 scaffolding protein derived peptide; CSP7; LTI-03

Latest Information Update: 14 Oct 2025

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At a glance

  • Originator Lung Therapeutics; University of Texas at Tyler
  • Developer Rein Therapeutics; University of Texas at Tyler
  • Class Alcohols; Amides; Amino acids; Antifibrotics; Benzene derivatives; Carboxylic acids; Peptides
  • Mechanism of Action Caveolin 1 replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Idiopathic pulmonary fibrosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Idiopathic pulmonary fibrosis

Most Recent Events

  • 09 Oct 2025 The European Medicines Agency (EMA) grants authorization to initiate the phase II RENEW trial in Germany and Poland
  • 22 Sep 2025 Chemical structure information added.
  • 17 Sep 2025 Pharmacodynamics data from a preclinical trial in idiopathic pulmonary fibrosis released by Rein Therapeutics

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