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AIM 001

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Drug Profile

AIM 001

Alternative Names: AdAPT-001; AIM-001; Multi-vax TGF-beta trap transgene expressing oncolytic smart virus; TGF- Trap Adenovirus; TGF-beta trap - EpicentRx

Latest Information Update: 01 Sep 2025

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At a glance

  • Originator EpicentRx
  • Class Antineoplastics; Immunotherapies; Oncolytic viruses
  • Mechanism of Action Cell death stimulants; Immunostimulants; Transforming growth factor beta inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Solid tumours

Most Recent Events

  • 30 May 2025 Efficacy and adverse event data from the phase I/II BETA-PRIME trial in Solid tumours presented at the 61st Annual Meeting of the American Society of Clinical Oncology (ASCO-2025)
  • 25 Apr 2025 Efficacy data from a phase I/II trial in Solid tumors presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 25 Apr 2025 Pharmacodynamics data from a pre-clinical trial in Sarcoma presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)

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