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Rosnilimab - AnaptysBio

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Drug Profile

Rosnilimab - AnaptysBio

Alternative Names: ANB-030

Latest Information Update: 19 Nov 2025

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At a glance

  • Originator AnaptysBio
  • Class Anti-inflammatories; Antibodies; Antirheumatics; Monoclonal antibodies; Skin disorder therapies
  • Mechanism of Action Programmed cell death 1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Alopecia areata; Rheumatoid arthritis
  • Phase I Autoimmune disorders
  • Discontinued Ulcerative colitis

Most Recent Events

  • 11 Nov 2025 Discontinued - Phase-II for Ulcerative colitis in USA, Georgia, Serbia, Spain, United Kingdom, Romania, Poland, Italy, Netherlands, Germany, France, Croatia, Canada, Austria, Bulgaria due to lack of adequate efficacy (SC)
  • 11 Nov 2025 Efficacy, safety and pharmacodynamic data from the phase II ROSETTA trial in Ulcerative colitis released by AnaptysBio
  • 11 Nov 2025 AnaptysBio terminates the phase II ROSETTA trial in Ulcerative colitis in USA, Austria, Bulgaria, Canada, Croatia, France, Germany, Italy, Netherlands, Poland, Romania, Spain, Georgia, Serbia and the United Kingdom as rosnilimab did not meet primary or secondary endpoints at week 12

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