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Sovilnesib - Volastra Therapeutics

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Drug Profile

Sovilnesib - Volastra Therapeutics

Alternative Names: AMG-650

Latest Information Update: 28 May 2025

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At a glance

  • Originator Amgen
  • Developer BeOne Medicines; Volastra Therapeutics
  • Class Antineoplastics; Benzamides; Piperidines; Pyrimidines; Small molecules; Spiro compounds
  • Mechanism of Action KIF18A protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Ovarian cancer
  • No development reported Solid tumours

Most Recent Events

  • 28 May 2025 No recent reports of development identified for phase-I development in Solid-tumours in China (PO, Tablet)
  • 28 May 2025 No recent reports of development identified for phase-I development in Solid-tumours(Inoperable/Unresectable, Late-stage disease, Metastatic disease, Recurrent, Second-line therapy or greater) in Australia (PO, Tablet)
  • 28 May 2025 No recent reports of development identified for phase-I development in Solid-tumours(Inoperable/Unresectable, Late-stage disease, Metastatic disease, Recurrent, Second-line therapy or greater) in Belgium (PO, Tablet)

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