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IO 202

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Drug Profile

IO 202

Alternative Names: IO-202

Latest Information Update: 26 Feb 2025

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At a glance

  • Originator Immune-Onc Therapeutics; University of Texas Health Science Center at Houston; University of Texas Southwestern Medical Center
  • Developer Immune-Onc Therapeutics
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; LILRB4 protein inhibitors; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Chronic myelomonocytic leukaemia; Acute myeloid leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Acute myeloid leukaemia; Chronic myelomonocytic leukaemia
  • Phase I Solid tumours
  • Preclinical Systemic lupus erythematosus

Most Recent Events

  • 31 Jan 2025 Immune-Onc Therapeutics completes a phase I trial in Acute myeloid leukaemia and Chronic myelomonocytic leukaemia (First-line therapy, Combination therapy, Monotherapy) in USA (IV) (NCT04372433)
  • 10 Dec 2024 Updated efficacy data from a phase Ib trial in Chronic myelomonocytic leukemia and Acute myeloid leukaemia released by Immune-Onc Therapeutics
  • 07 Dec 2024 Updated efficacy and adverse events data from a phase I trial in Chronic myelomonocytic leukemia and Acute myeloid leukaemia presented at the 66th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2024)

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