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Molnupiravir - Emory University/Georgia State University/Merck & Co/Ridgeback Biotherapeutics

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Drug Profile

Molnupiravir - Emory University/Georgia State University/Merck & Co/Ridgeback Biotherapeutics

Alternative Names: EIDD-2801; LAGEVRIO; MK-4482; Molxvir; Movfor

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Emory University; Georgia State University
  • Developer Emory University; Hetero Labs; Merck & Co; Merck Sharp & Dohme; Ridgeback Biotherapeutics
  • Class Antivirals; Esters; Hydroxylamines; Pyrimidinones; Ribonucleosides; Small molecules
  • Mechanism of Action Virus replication inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed COVID 2019 infections
  • Phase II Respiratory syncytial virus infections
  • Phase I Influenza virus infections; Renal failure
  • Preclinical Chikungunya virus infections; Eastern equine encephalomyelitis; Ebola virus infections; Middle East respiratory syndrome coronavirus; Severe acute respiratory syndrome; Venezuelan equine encephalomyelitis

Most Recent Events

  • 21 Aug 2023 Phase-I clinical trials in Influenza virus infections (In volunteers) in United Kingdom (PO) (NCT05818124)
  • 21 Jun 2023 Regulatory submission withdrawn for COVID-2019 infections in European Union (PO)
  • 21 Jun 2023 Merck Sharp & Dohme withdraws a marketing authorisation application for molnupiravir for COVID-19 infections in the European Union
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