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Durcabtagene autoleucel - Novartis Pharmaceuticals

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Drug Profile

Durcabtagene autoleucel - Novartis Pharmaceuticals

Alternative Names: Anti-BCMA CAR-T Cell Therapy - Novartis Pharmaceuticals; BCMA-directed CAR-T Cell Therapy - Novartis Pharmaceuticals; PHE-885

Latest Information Update: 04 Feb 2025

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At a glance

  • Originator Novartis Pharmaceuticals
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Multiple myeloma

Most Recent Events

  • 07 Dec 2024 Updated pharmacokinetics data from a phase I trial in Multiple myeloma presented at the trial at the 66th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2024)
  • 03 May 2024 Phase-II clinical trials in Multiple myeloma (Second-line therapy or greater) in USA, Brazil, Canada, France, Germany, Greece, Israel, Japan, Saudi Arabia, United Kingdom (IV) (NCT05172596)
  • 09 Dec 2023 Updated pharmacokinetics data from a phase I trial in Multiple myeloma presented at the trial at the 65th American Society of Hematology Annual Meeting and Exposition (ASH-2023)

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