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AL 008

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Drug Profile

AL 008

Alternative Names: add Anti-SIRP-alpha antibody - Alector/Innovent Biologics; AL 008; IBI-397

Latest Information Update: 28 Apr 2024

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At a glance

  • Originator Alector
  • Developer Alector; Innovent Biologics
  • Class Antibodies; Antineoplastics; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; CD47 antigen inhibitors; Immunostimulants; SIRPA protein inhibitors; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Cancer

Most Recent Events

  • 28 Apr 2024 No recent reports of development identified for preclinical development in Cancer in USA (Parenteral)
  • 15 Sep 2023 Discontinued - Phase-I for Cancer (Combination therapy, Late-stage disease, Metastatic disease, Recurrent, Second-line therapy or greater) in China (Parenteral) (NCT05245916)
  • 31 Aug 2023 Discontinued - Phase-I for Cancer (Late-stage disease, Metastatic disease, Monotherapy, Recurrent, Second-line therapy or greater) in China (Parenteral) (NCT05245916)

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