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Aplitabart - IGM Biosciences

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Drug Profile

Aplitabart - IGM Biosciences

Alternative Names: IGM-8444

Latest Information Update: 22 Aug 2024

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At a glance

  • Originator IGM Biosciences
  • Class Antibodies; Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action TRAIL receptor 2 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Colorectal cancer; Non-Hodgkin's lymphoma; Solid tumours
  • Suspended Acute myeloid leukaemia

Most Recent Events

  • 14 Aug 2024 IGM Biosciences completes enrollment in phase I trial in Colorectal cancer (Late-stage disease, Metastatic disease, Monotherapy, Combination therapy, Second-line therapy or greater) in the US, Asia and Europe (IV)
  • 05 Apr 2024 Pharmacodynamics data from preclinical trials in Solid tumours presented at the 115th Annual Meeting of the American Association for Cancer Research (AACR-2024)
  • 05 Dec 2023 Suspended - Phase-I for Acute myeloid leukaemia (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in Australia (IV)

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