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IGM 7354

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Drug Profile

IGM 7354

Alternative Names: Anti-PD-L1 x IL-15 Cytokine Fusion IgM; IGM-7354; IL-15 x PD-L1 bispecific IgM antibody

Latest Information Update: 06 Aug 2024

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At a glance

  • Originator IGM Biosciences
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; CD8 positive T lymphocyte stimulants; Natural killer cell stimulants; Programmed cell death-1 ligand-1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Suspended Haematological malignancies; Solid tumours

Most Recent Events

  • 31 May 2024 IGM Biosciences completes phase-I clinical trials in Solid tumours (Second-line therapy or greater) in USA (IV) (NCT05702424)
  • 05 Dec 2023 Suspended - Phase-I for Solid tumours (Second-line therapy or greater) in USA (IV)
  • 05 Dec 2023 Suspended - Preclinical for Haematological malignancies in USA (IV)

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