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Debio 1453

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Drug Profile

Debio 1453

Alternative Names: Debio-1453; Debio-1453P

Latest Information Update: 22 Jan 2026

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At a glance

  • Originator Debiopharm; Nobelex Biotech
  • Class Antibacterials; Benzofurans; Naphthyridines; Small molecules
  • Mechanism of Action Enoyl ACP reductase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Gonorrhoea

Most Recent Events

  • 13 Jan 2026 Debiopharm and Global Antibiotic Research & Development Partnership agree to co-develop Debio 1453 for Gonorrhea
  • 04 Sep 2025 Chemical structure information added.
  • 25 Jun 2025 Debiopharm plans a first-in-human phase I trial in Healthy adult volunteers (PO, Solution) (NCT07035769) (EudraCT2024-519328-26)

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