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Niclosamide - TFF Pharmaceuticals

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Drug Profile

Niclosamide - TFF Pharmaceuticals

Latest Information Update: 02 Jun 2025

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At a glance

  • Originator TFF Pharmaceuticals
  • Class Anthelmintics; Anti-inflammatories; Antibacterials; Antineoplastics; Antivirals; Benzamides; Chlorophenols; Nitrobenzenes; Skin disorder therapies; Small molecules
  • Mechanism of Action Mitochondrial oxidative phosphorylation uncouplers; MTOR protein inhibitors; Notch signalling pathway inhibitors; STAT3 transcription factor inhibitors; Virus internalisation inhibitors; Virus replication inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Discontinued COVID 2019 infections

Most Recent Events

  • 03 Mar 2025 Discontinued - Phase-I for COVID-2019 infections (In volunteers, In adults) in Canada (Inhalation)
  • 03 Mar 2025 Discontinued - Preclinical for COVID-2019 infections in USA (PO)
  • 28 Dec 2024 No recent reports of development identified for phase-I development in COVID-2019-infections(In volunteers, In adults) in Canada (Inhalation, Powder)

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