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JS 108

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Drug Profile

JS 108

Alternative Names: DAC 002; DAC-002/JS108; JS-108

Latest Information Update: 28 Nov 2023

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At a glance

  • Originator Hangzhou DAC Biotech
  • Developer Hangzhou DAC Biotech; Shanghai Junshi Biosciences
  • Class Antineoplastics; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action Tubulin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Solid tumours

Most Recent Events

  • 28 Nov 2023 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (IV, Injection)
  • 14 Jun 2023 Shanghai Junshi Bioscience terminates phase I trial in Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (IV), as the sponsor adjusted the study development plan (NCT04601285)
  • 16 Feb 2023 US FDA approves IND application for JS 108 in Solid tumours (Hangzhou DAC Biotech pipeline, February 2023)

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