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AV 353

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Drug Profile

AV 353

Alternative Names: Anti-Notch 3 mAb; AV-353; Notch 3 MAb

Latest Information Update: 28 Aug 2024

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At a glance

  • Originator AVEO Oncology
  • Class Antihypertensives; Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Notch-3 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • No development reported Cancer
  • Discontinued Pulmonary arterial hypertension

Most Recent Events

  • 28 Aug 2024 No recent reports of development identified for preclinical development in Cancer in USA (Parenteral)
  • 03 Aug 2022 AV 353 is still in preclinical trials for Cancer in US (Parenteral) (AVEO Oncology pipeline, August 2022)
  • 28 Apr 2022 No recent reports of development identified for preclinical development in Cancer in USA (Parenteral)

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