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DSP 0390

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Drug Profile

DSP 0390

Alternative Names: DSP-0390; TP-0390

Latest Information Update: 13 Aug 2026

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At a glance

  • Originator Sumitomo Dainippon Pharma; Tolero Pharmaceuticals
  • Developer Sumitomo Pharma
  • Class Antineoplastics; Small molecules
  • Mechanism of Action EBP protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Brain cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Glioma; Small cell lung cancer

Most Recent Events

  • 03 Aug 2026 Phase-I clinical trials in Small cell lung cancer (Late-stage disease, Combination therapy) in USA (PO) (NCT07545954)
  • 22 Apr 2026 Washington University School of Medicine in collaboration with Sumitomo Pharma plans a phase I trial for Small cell lung cancer (Combination therapy, Second-line therapy or greater, Late-stage disease) in USA (PO) (NCT07545954)
  • 29 Apr 2025 DSP 0390 is still in phase I trials for Glioma (Recurrent) in USA and Japan (PO) (Sumitomo Pharma pipeline, April 2025)

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