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Cibotercept - Keros Therapeutics

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Drug Profile

Cibotercept - Keros Therapeutics

Alternative Names: KER-012; RKER 012

Latest Information Update: 09 Jun 2025

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At a glance

  • Originator Keros Therapeutics
  • Class Antihypertensives; Heart failure therapies; Immunoglobulin Fc fragments; Osteoporosis therapies; Recombinant fusion proteins
  • Mechanism of Action Transforming growth factor beta inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Chronic heart failure
  • Phase I Osteoporosis
  • Preclinical Osteogenesis imperfecta
  • Discontinued Pulmonary arterial hypertension

Most Recent Events

  • 29 May 2025 Discontinued - Phase-II for Pulmonary arterial hypertension in Australia (SC)
  • 29 May 2025 Discontinued - Phase-II for Pulmonary arterial hypertension in Brazil (SC)
  • 29 May 2025 Discontinued - Phase-II for Pulmonary arterial hypertension in France (SC)

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