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ION 537

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Drug Profile

ION 537

Alternative Names: ION-537

Latest Information Update: 28 Jan 2024

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At a glance

  • Originator Ionis Pharmaceuticals; University of Texas M. D. Anderson Cancer Center
  • Class Antineoplastics; Antisense oligonucleotides
  • Mechanism of Action RNA interference; YAP1 (Yes-associated) protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Cancer

Highest Development Phases

  • No development reported Solid tumours

Most Recent Events

  • 28 Jan 2024 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV, Injection)
  • 19 Oct 2022 Ionis Pharmaceuticals completes a phase-I trial in Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV) (NCT04659096)
  • 05 Jan 2021 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV) (NCT04659096)

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