4A 10
Alternative Names: 4A-10; 4A10 antibody therapy - Allterum TherapeuticsLatest Information Update: 23 Jun 2026
At a glance
- Originator National Cancer Institute (USA)
- Developer Allterum Therapeutics
- Class Antineoplastics; Monoclonal antibodies
- Mechanism of Action Antibody-dependent cell cytotoxicity; Interleukin 7 receptor alpha subunit inhibitors
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Orphan Drug Status
Yes - Precursor cell lymphoblastic leukaemia-lymphoma
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I Precursor cell lymphoblastic leukaemia-lymphoma
- Preclinical Precursor T-cell lymphoblastic leukaemia-lymphoma
Most Recent Events
- 01 Jun 2026 Phase-I clinical trials in Precursor cell lymphoblastic leukaemia-lymphoma (Second-line therapy or greater) in USA (IV, Infusion) (NCT07586618)
- 11 Nov 2025 Preclinical trials in Precursor cell lymphoblastic leukaemia-lymphoma in USA (Parenteral) prior to November 2025
- 11 Nov 2025 4A 10 receives Fast Track designation for Precursor cell lymphoblastic leukaemia-lymphoma (Second-line therapy or greater) (Parenteral) in USA