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4A 10

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Drug Profile

4A 10

Alternative Names: 4A-10; 4A10 antibody therapy - Allterum Therapeutics

Latest Information Update: 04 Jul 2025

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At a glance

  • Originator National Cancer Institute (USA)
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Precursor T-cell lymphoblastic leukaemia-lymphoma
  • New Molecular Entity Yes

Highest Development Phases

  • Research Precursor T-cell lymphoblastic leukaemia-lymphoma

Most Recent Events

  • 25 Apr 2025 Pharmacodynamic data from a preclinical trial in Acute lymphoblastic leukemia presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 08 Oct 2024 4A 10 is still in preclinical trials for Precursor T-cell lymphoblastic leukaemia-lymphoma in the US (Parenteral)
  • 08 Oct 2024 4A 10 receives Orphan Drug status for Precursor T-cell lymphoblastic leukaemia-lymphoma in USA

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