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Nintedanib inhalation - Avalyn Pharmaceuticals

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Drug Profile

Nintedanib inhalation - Avalyn Pharmaceuticals

Alternative Names: Aerosolized nintedanib - Avalyn Pharma; AP 02 DP; AP-02; AP02-DP-Inhaled Nintedanib–dry powder; AP02-Inhaled Nintedanib

Latest Information Update: 16 Aug 2024

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At a glance

  • Originator Avalyn Pharma
  • Class Acetamides; Antifibrotics; Antineoplastics; Esters; Indoles; Piperazines; Skin disorder therapies; Small molecules
  • Mechanism of Action Fms-like tyrosine kinase 3 inhibitors; Lymphocyte specific protein tyrosine kinase p56(lck) inhibitors; Lyn protein-tyrosine kinase inhibitors; Platelet-derived growth factor alpha receptor antagonists; Platelet-derived growth factor beta receptor antagonists; Src-family kinase inhibitors; Type 1 fibroblast growth factor receptor antagonists; Type 3 fibroblast growth factor receptor antagonists; Type-2 fibroblast growth factor receptor antagonists; Vascular endothelial growth factor receptor-1 antagonists; Vascular endothelial growth factor receptor-2 antagonists; Vascular endothelial growth factor receptor-3 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I Idiopathic pulmonary fibrosis; Interstitial lung diseases; Pulmonary fibrosis

Most Recent Events

  • 12 Aug 2024 Phase-I clinical trials in Idiopathic pulmonary fibrosis (In volunteers) in Australia (Inhalation) (ACTRN12624000825550)
  • 19 Apr 2024 Phase I clinical development of Nintedanib inhalation - Avalyn Pharmaceuticals is ongoing in Australia (ACTRN12620001141932) (Avalyn pharma pipeline, April 2024)
  • 28 Jan 2024 No recent reports of development identified for phase-I development in Interstitial lung diseases in Australia (Inhalation)

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