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TGTX 106

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Drug Profile

TGTX 106

Alternative Names: TGTX-106; TSHA-106

Latest Information Update: 28 May 2024

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At a glance

  • Originator University of North Carolina at Chapel Hill; University of Texas Southwestern Medical Center
  • Developer Taysha Gene Therapies; University of Texas Southwestern Medical Center
  • Class RNA
  • Mechanism of Action RNA interference; UBE3A protein expression stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Angelman syndrome

Most Recent Events

  • 28 May 2024 No recent reports of development identified for preclinical development in Angelman-syndrome in USA (Intrathecal)
  • 31 Dec 2023 Taysha Gene Therapies has two pending patent applications worldwide for TGTX 106 in-licensed from The Board of Regents of The University of Texas System
  • 31 Dec 2022 Taysha Gene Therapies has patent pending for RNA interference (RNAi) constructs targeting UBE3A in-licensed from The Board of Regents of The University of Texas System worldwide

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